Mutoh T, Narita M, Nagai T, Furudate S, Taniuchi S, Kudo M, Fujii H.
Clinical Images: Multiple punched-out ulcerations on the abdomen in anti-melanoma differentiation-associated gene 5 dermatomyositis
Arthritis Rheumatol. 2024 Jan;76(1):150-151. doi: 10.1002/art.42521. Epub 2023 Jul 11.
PMID: 37096454 No abstract available.
Yamato M, Shirai T, Sato H, Ishii T, Fujii H.
First reported case of pulmonary arteritis in patients with relapsing polychondritis
Rheumatology (Oxford). 2024 Jan 4;63(1):e9-e11. doi: 10.1093/rheumatology/kead300.
PMID: 37326857 No abstract available.
Khanna D, Kramer F, Höfler J, Ghadessi M, Sandner P, Allanore Y, Denton CP, Kuwana M, Matucci-Cerinic M, Pope JE, Atsumi T, Bečvář R, Czirják L, De Langhe E, Hachulla E, Ishii T, Ishikawa O, Johnson SR, Riccieri V, Schiopu E, Silver RM, Smith V, Stagnaro C, Steen V, Stevens W, Szücs G, Truchetet ME, Wosnitza M, Distler O.
Biomarker analysis from the phase 2b randomized placebo-controlled trial of riociguat in early diffuse cutaneous systemic sclerosis
Rheumatology (Oxford). 2024 Mar 9:keae150. doi: 10.1093/rheumatology/keae150. Online ahead of print.
PMID: 38460548
Yamato M, Shirai T, Ishii Y, Sato H, Ishii T, Fujii H.
Impact of subcutaneous belimumab on disease activity, patient satisfaction, and metabolic profile in long-lasting systemic lupus erythematosus
Clin Rheumatol. 2024 Mar;43(3):1023-1035. doi: 10.1007/s10067-024-06904-9. Epub 2024 Feb 9.
PMID: 38334937
Sugihara T, Yoshifuji H, Uchida HA, Maejima Y, Watanabe Y, Tanemoto K, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Niiro H, Ishii T, Nakaoka Y, Harigai M.
Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis
Mod Rheumatol. 2024 Mar 28;34(3):568-575. doi: 10.1093/mr/road046.
PMID: 37225423
Saito I, Shirai T, Sato H, Ishii T, Fujii H.
Enthesitis as an initial presentation of vascular Behçet's syndrome: a case-based review
Rheumatol Int. 2024 May 7. doi: 10.1007/s00296-024-05607-3. Online ahead of print.
PMID: 38713409 Review.
Ishikawa Y, Yoshida H, Yoshifuji H, Ohmura K, Origuchi T, Ishii T, Mimori T, Morinobu A, Shiokawa M, Terao C.
Anti-integrin αvβ6 antibody in Takayasu arteritis patients with or without ulcerative colitis
Front Immunol. 2024 May 9;15:1387516. doi: 10.3389/fimmu.2024.1387516. eCollection 2024.
PMID: 38784377 Free PMC article.
2023年
Shirai T, Suzuki J, Kuniyoshi S, Tanno Y, Fujii H.
Granulomatosis with polyangiitis following Pfizer-BioNTech COVID-19 vaccination
Mod Rheumatol Case Rep. 2023 Jan 3;7(1):127-129. doi: 10.1093/mrcr/rxac016.
PMID: 35246689 Free PMC article.
Mutoh T, Ohashi K, Nagai T, Sugiura A, Kudo M, Fujii H.
Upfront rituximab therapy for thrombotic thrombocytopenic purpura in systemic lupus erythematosus: a case-based review.
Rheumatol Int. 2023 Feb;43(2):373-381. doi: 10.1007/s00296-022-05182-5. Epub 2022 Aug 12.
PMID: 35962219 Review.
Shirai T, Machiyama T, Sato H, Ishii T, Fujii H.
Intensive induction therapy combining tofacitinib, rituximab and plasma exchange in severe anti-melanoma differentiation-associatedprotein-5 antibody-positive dermatomyositis
Clin Exp Rheumatol. 2023 Mar;41(2):291-300. doi: 10.55563/clinexprheumatol/8kulbf. Epub 2023 Jan 24.
PMID: 36700661 Free article.
Shirai T, Sato H, Ishii T, Fujii H.
Dysbiosis in Takayasu arteritis complicated with infectious endocarditis following tocilizumab administration.
Scand J Rheumatol. 2023 Mar;52(2):224-226. doi: 10.1080/03009742.2022.2124620. Epub 2022 Oct 18.
PMID: 36255303 No abstract available.
Kakuta Y, Shirai T, McGovern DPB, Braun J, Fujii H, Masamune A.
Novel Diagnostic Autoantibodies Against Endothelial Protein C Receptor in Patients With Ulcerative Colitis.
Clin Gastroenterol Hepatol. 2023 Mar;21(3):844-846. doi: 10.1016/j.cgh.2021.12.035. Epub 2021 Dec 28.
PMID: 34971808
Akaishi T, Onodera T, Takahashi T, Harigae H, Ishii T.
Acute Adverse Events at a Mass Vaccination Site after the Third and Fourth COVID-19 Vaccinations in Japan
Tohoku J Exp Med. 2023 Mar 9;259(4):263-271. doi: 10.1620/tjem.2023.J002. Epub 2023 Jan 13.
PMID: 36642506 Free article.
Ishii T, Sato Y, Munakata Y, Kajiwara M, Takahashi Y, van Hoogstraten H, Xu C, Kato N, Takahashi T.
Pharmacokinetics, pharmacodynamics, and safety of single-dose subcutaneous sarilumab with or without methotrexate in Japanese patients with rheumatoid arthritis: Two single-dose studies
Mod Rheumatol. 2023 Mar 2;33(2):279-291. doi: 10.1093/mr/roac036.
PMID: 35445719 Clinical Trial.
Mutoh T, Narita M, Nagai T, Furudate S, Taniuchi S, Kudo M, Fujii H.
Clinical Images: Multiple punched-out ulcerations on the abdomen in anti-melanoma differentiation-associated gene 5 dermatomyositis
Arthritis Rheumatol. 2023 Apr 25. doi: 10.1002/art.42521. Online ahead of print.
PMID: 37096454 No abstract available.
Miyata M, Hirabayashi Y, Munakata Y, Urata Y, Saito K, Okuno H, Yoshida M, Kodera T, Watanabe R, Miyamoto S, Ishii T, Nakazawa S, Takemori H, Ando T, Kanno T, Komagamine M, Kato I, Takahashi Y, Komatsuda A, Endo K, Murai C, Takakubo Y, Miura T, Sato Y, Ichikawa K, Konta T, Chiba N, Muryoi T, Kobayashi H, Fujii H, Sekiguchi Y, Hatakeyama A, Ogura K, Sakuraba H, Asano T, Kanazawa H, Suzuki E, Takasaki S, Asakura K, Suzuki Y, Takagi M, Nakayama T, Watanabe H, Miura K, Mori Y; Michinoku Tocilizumab Study Group.
Feasibility of methotrexate discontinuation following tocilizumab and methotrexate combination therapy in patients with long-standing and advanced rheumatoid arthritis: a 3-year observational cohort study
Fukushima J Med Sci. 2023 Apr 5;69(1):11-20. doi: 10.5387/fms.2022-06. Epub 2023 Mar 30.
PMID: 36990790 Free PMC article.
Ichimura H, Ichikawa S, Ono K, Inokura K, Hoshi Y, Shirai T, Fukuhara N, Yokoyama H, Fujii H, Harigae H.
Severe Bone Marrow Aplasia Following Macrophage Activation Syndrome in Systemic Lupus Erythematosus.
Tohoku J Exp Med. 2023 May 11. doi: 10.1620/tjem.2023.J037. Online ahead of print.
PMID: 37164698 Free article. No abstract available.
Sugihara T, Yoshifuji H, Uchida HA, Maejima Y, Watanabe Y, Tanemoto K, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Niiro H, Ishii T, Nakaoka Y, Harigai M.
Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis
Mod Rheumatol. 2023 May 24:road046. doi: 10.1093/mr/road046. Online ahead of print.
PMID: 37225423
Akaishi T, Tokuda K, Katsumi M, Fujimaki SI, Aoyagi T, Harigae H, Ishii T.
Blood Culture Result Profile in Patients With Central Line-Associated Bloodstream Infection (CLABSI): A Single-Center Experience
Cureus. 2023 Jun 9;15(6):e40202. doi: 10.7759/cureus.40202. eCollection 2023 Jun.
PMID: 37435240
Free PMC article.
Yamato M, Shirai T, Sato H, Ishii T, Fujii H.
First reported case of pulmonary arteritis in patients with relapsing polychondritis
Rheumatology (Oxford). 2023 Jun 16:kead300. doi: 10.1093/rheumatology/kead300. Online ahead of print.
PMID: 37326857 No abstract available.
Shirai T.
Common Autoantibody among Takayasu Arteritis and Ulcerative Colitis: A Possible Pathophysiology That Includes Gut-Vessel Connection in Vascular Inflammation
JMA J. 2023 Jul 14;6(3):265-273. doi: 10.31662/jmaj.2023-0038. Epub 2023 May 29.
PMID: 37560375 Free PMC article. Review.
Shirai T, Watanabe S, Shinozaki NO, Baba K, Yamasaki H, Ishii T, Fujii H.
Common dysbiosis features between patients of different social environments in Takayasu arteritis: comment on the article by Fan et al
Arthritis Rheumatol. 2023 Jul;75(7):1291-1292. doi: 10.1002/art.42438. Epub 2023 May 31.
PMID: 36622341 No abstract available.
Maeda A, Tsuchida N, Uchiyama Y, Horita N, Kobayashi S, Kishimoto M, Kobayashi D, Matsumoto H, Asano T, Migita K, Kato A, Mori I, Morita H, Matsubara A, Marumo Y, Ito Y, Machiyama T, Shirai T, Ishii T, Kishibe M, Yoshida Y, Hirata S, Akao S, Higuchi A, Rokutanda R, Nagahata K, Takahashi H, Katsuo K, Ohtani T, Fujiwara H, Nagano H, Hosokawa T, Ito T, Haji Y, Yamaguchi H, Hagino N, Shimizu T, Koga T, Kawakami A, Kageyama G, Kobayashi H, Aoki A, Mizokami A, Takeuchi Y, Motohashi R, Hagiyama H, Itagane M, Teruya H, Kato T, Miyoshi Y, Kise T, Yokogawa N, Ishida T, Umeda N, Isogai S, Naniwa T, Yamabe T, Uchino K, Kanasugi J, Takami A, Kondo Y, Furuhashi K, Saito K, Ohno S, Kishimoto D, Yamamoto M, Fujita Y, Fujieda Y, Araki S, Tsushima H, Misawa K, Katagiri A, Kobayashi T, Hashimoto K, Sone T, Hidaka Y, Ida H, Nishikomori R, Doi H, Fujimaki K, Akasaka K, Amano M, Matsushima H, Kashino K, Ohnishi H, Miwa Y, Takahashi N, Takase-Minegishi K, Yoshimi R, Kirino Y, Nakajima H, Matsumoto N.
Efficient detection of somatic UBA1 variants and clinical scoring system predicting patients with variants in VEXAS syndrome
Rheumatology (Oxford). 2023 Aug 22:kead425. doi: 10.1093/rheumatology/kead425. Online ahead of print.
PMID: 37606963
Kawahata K, Ishii T, Gono T, Tsuchiya Y, Ohashi H, Yoshizawa K, Zheng R, Ayabe M, Nishikawa K.
Phase 3, multicentre, randomised, double-blind, placebo-controlled, parallel-group study of ustekinumab in Japanese patients with active polymyositis and dermatomyositis who have not adequately responded to one or more standard-of-care treatments
RMD Open. 2023 Aug;9(3):e003268. doi: 10.1136/rmdopen-2023-003268.
PMID: 37652554 Free PMC article. Clinical Trial.
Tanaka Y, Atsumi T, Okada M, Miyamura T, Ishii T, Nishiyama S, Matsumura R, Kawakami A, Hayashi N, Abreu G, Yavuz S, Lindholm C, Al-Mossawi H, Takeuchi T.
The long-term safety and tolerability of anifrolumab for patients with systemic lupus erythematosus in Japan: TULIP-LTE subgroup analysis
Mod Rheumatol. 2023 Sep 14:road092. doi: 10.1093/mr/road092. Online ahead of print.
PMID: 37706527
Katakura T, Shirai T, Sato H, Ishii T, Fujii H.
Successful management of interstitial lung disease in dermatomyositis complicated by malignancy: a case-based review
Rheumatol Int. 2023 Sep 8. doi: 10.1007/s00296-023-05442-y. Online ahead of print.
PMID: 37682289 Review.
Yasaka K, Yamazaki T, Sato H, Shirai T, Cho M, Ishida K, Ito K, Tanaka T, Ogasawara K, Harigae H, Ishii T, Fujii H.
Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus
Arthritis Res Ther. 2023 Oct 16;25(1):200. doi: 10.1186/s13075-023-03186-5.
PMID: 37840148 Free PMC article.
Shirota S, Shirai T, Mori K, Inoue J, Sato H, Ishii T, Fujii H.
Comment on: A case of vanishing bile duct syndrome during treatment of microscopic polyangiitis with avacopan
Rheumatology (Oxford). 2023 Oct 25:kead561. doi: 10.1093/rheumatology/kead561. Online ahead of print.
PMID: 37878792 No abstract available.
Mutoh T, Shrai T, Fujii H.
Comment on: Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis
Rheumatology (Oxford). 2023 Nov 2;62(11):e323-e324. doi: 10.1093/rheumatology/keac589.
PMID: 36218414 No abstract available.
Ishii T, Kunishige H, Kobayashi T, Hayashi E, Komatsubara M, Ishii T, Alfonso-Cristancho R, Tamaoki J, Howarth P.
Real-world safety and effectiveness of mepolizumab for patients with eosinophilic granulomatosis with polyangiitis (EGPA) in Japan: 48-week interim analysis of the MARS study
Mod Rheumatol. 2023 Dec 8:road109. doi: 10.1093/mr/road109. Online ahead of print.
PMID: 38100679
ここまできた分子標的薬・抗体製剤の最新情報from A to Z(No.18) 血管炎の分子標的薬
石井 智徳(東北大学病院 臨床研究推進センター臨床研究実施部門)
日本医師会雑誌(0021-4493)151巻11号 Page1972-1973(2023.02)
論文種類：解説
Nono Ito , Tsuyoshi Shirai , Takafumi Toyohara , Hideaki Hashimoto , Hiroko Sato , Hiroshi Fujii , Tomonori Ishii , Hideo Harigae
Coexistence of IgA nephropathy and renal artery stenosis in Takayasu arteritis: case report and literature review
Rheumatol Int. 2022 Jan 11. doi: 10.1007/s00296-021-05066-0. Online ahead of print.
Imai K, Ishii T, Nonoyama S, Yasumi T, Kanegane H, Fukushima T, Matsumaru M, Akasaki T, Usui H.
Real-world results with IgPro20 for hypo- or agammaglobulinemia in Japan.
Pediatr Int. 2022 Jan;64(1):e15362. doi: 10.1111/ped.15362.
PMID: 36151913 Free PMC article.
Machi Kiyohara , Tsuyoshi Shirai , Shuhei Nishiyama , Hiroko Sato , Hiroshi Fujii , Tomonori Ishii , Hideo Harigae
Hypertrophic Pachymeningitis Development in Eosinophilic Granulomatosis with Polyangiitis at Relapse of Disease: A Case-Based Review
Tohoku J Exp Med. 2022 Mar;256(3):241-247. doi: 10.1620/tjem.256.241.
Mutoh T, Nagai T, Shirai T, Okazaki S, Sato H, Fujii H.
Predictive factors for retention of golimumab over a median 4-year duration in Japanese patients with rheumatoid arthritis in a real-world setting: A retrospective study and literature review.
Int J Rheum Dis. 2022 Mar;25(3):335-343. doi: 10.1111/1756-185X.14281. Epub 2022 Jan 6.
PMID: 34989482
Kae Ishii , Tsuyoshi Shirai , Yoichi Kakuta , Tomoaki Machiyama , Hiroko Sato , Tomonori Ishii , Hideo Harigae , Hiroshi Fujii
Development of severe colitis in Takayasu arteritis treated with tocilizumab
Clin Rheumatol. 2022 Jun;41(6):1911-1918. doi: 10.1007/s10067-022-06108-z. Epub 2022 Feb 21.
Chikaho Akiyama , Tsuyoshi Shirai , Hiroko Sato , Hiroshi Fujii , Tomonori Ishii , Hideo Harigae
Association of various myositis-specific autoantibodies with dermatomyositis and polymyositis triggered by pregnancy
Rheumatol Int. 2022 Jul;42(7):1271-1280. doi: 10.1007/s00296-021-04851-1. Epub 2021 Apr 10.
Itoi S, Takahashi N, Saito H, Miyata Y, Su MT, Kezuka D, Itagaki F, Endo S, Fujii H, Harigae H, Sakamoto Y, Takai T.
Myeloid immune checkpoint ILT3/LILRB4/gp49B can co-tether fibronectin with integrin on macrophages.
Int Immunol. 2022 Jul 26;34(8):435-444. doi: 10.1093/intimm/dxac023.
PMID: 35689642
Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M.
Establishing clinical remission criteria and the framework of a treat-to-target algorithm for Takayasu arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour and Welfare for intractable vasculitis.
Mod Rheumatol. 2022 Aug 20;32(5):930-937. doi: 10.1093/mr/roab081.
PMID: 34850081
Ishikawa T, Suzuki J, Shirai T, Koizumi S, Tsuchiya Y, Hishinuma K, Nakamura Y, Katori Y.
Presence of Phlebitis in Aseptic Nasal Septal Abscess Complicated with Ulcerative Colitis; Possible Association with Granulomatosis with Polyangiitis: A Case Report.
Tohoku J Exp Med. 2022 Aug 5;258(1):29-34. doi: 10.1620/tjem.2022.J053. Epub 2022 Jun 30.
PMID: 35768225 Free article.
Akaishi T, Onodera T, Takahashi T, Harigae H, Ishii T.
Reports of acute adverse events in mRNA COVID-19 vaccine recipients after the first and second doses in Japan.
Sci Rep. 2022 Sep 15;12(1):15510. doi: 10.1038/s41598-022-19936-5.
PMID: 36109582 Free PMC article.
Kamogawa Y, Akita K, Sato H, Shirai T, Ishii T, Harigae H, Fujii H.
Sjögren's Syndrome Presenting with Temporary Hemiplegia Mimicking Transient Ischemic Attack.
Tohoku J Exp Med. 2022 Oct 26;258(3):207-211. doi: 10.1620/tjem.2022.J079. Epub 2022 Sep 23.
PMID: 36155592 Free article.
Mutoh T, Shrai T, Fujii H.
Comment on: Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis.
Rheumatology (Oxford). 2022 Oct 11:keac589. doi: 10.1093/rheumatology/keac589. Online ahead of print.
PMID: 36218414 No abstract available.
Mutoh T, Shirai T, Sato H, Fujii H, Ishii T, Harigae H.
Multi-targeted therapy for refractory eosinophilic granulomatosis with polyangiitis characterized by intracerebral hemorrhage and cardiomyopathy: a case-based review.
Rheumatol Int. 2022 Nov;42(11):2069-2076. doi: 10.1007/s00296-021-04950-z. Epub 2021 Jul 21.
PMID: 34287685 Review.
Kimura N, Kawahara T, Uemura Y, Atsumi T, Sumida T, Mimura T, Kawaguchi Y, Amano H, Iwasaki Y, Kaneko Y, Matsui T, Muro Y, Imura Y, Kanda T, Tanaka Y, Kawakami A, Jinnin M, Ishii T, Hiromura K, Miwa Y, Nakajima H, Kuwana M, Nishioka Y, Morinobu A, Kameda H, Kohsaka H.
Branched chain amino acids in the treatment of polymyositis and dermatomyositis: a phase II/III, multi-centre, randomized controlled trial.
Rheumatology (Oxford). 2022 Nov 2;61(11):4445-4454. doi: 10.1093/rheumatology/keac101.
PMID: 35179548 Clinical Trial.
Kanae Akita , Ken Yasaka , Tsuyoshi Shirai , Tomonori Ishii , Hideo Harigae , Hiroshi Fujii
Interferon α Enhances B Cell Activation Associated With FOXM1 Induction: Potential Novel Therapeutic Strategy for Targeting the Plasmablasts of Systemic Lupus Erythematosus
Front Immunol. 2021 Feb 3;11:498703. doi: 10.3389/fimmu.2020.498703. eCollection 2020.
Hiroko Sato , Tsuyoshi Shirai , Hiroshi Fujii , Tomonori Ishii , Hideo Harigae
Cyclophosphamide-associated enteritis presenting with severe protein-losing enteropathy in granulomatosis with polyangiitis: A case report
World J Gastroenterol. 2021 May 28;27(20):2657-2663. doi: 10.3748/wjg.v27.i20.2657.
Tomoyuki Mutoh , Tsuyoshi Shirai , Hiroko Sato , Hiroshi Fujii , Tomonori Ishii , Hideo Harigae
Multi-targeted therapy for refractory eosinophilic granulomatosis with polyangiitis characterized by intracerebral hemorrhage and cardiomyopathy: a case-based review
Rheumatol Int. 2021 Jul 21. doi: 10.1007/s00296-021-04950-z. Online ahead of print.
T Shirai , H Sato , H Fujii , T Ishii , H Harigae
The feasible maintenance dose of corticosteroid in Takayasu arteritis in the era of biologic therapy
Scand J Rheumatol. 2021 Nov;50(6):462-468. doi: 10.1080/03009742.2021.1881155. Epub 2021 Mar 17.
Mutoh T, Shirai T, Fujii H, Ishii T, Harigae H.
Insufficient use of corticosteroids without immunosuppressants results in higher relapse in Takayasu arteritis.
J Rheumatol. 2020 Feb;47(2):255-263. doi: 10.3899/jrheum.181219. Epub 2019 May 15.
Kondo H, Watanabe R, Okazaki S, Kuriyama K, Harigae H, Fujii H.
Coexistence of rheumatoid arthritis and systemic lupus erythematosus is still rare in the biologic era: Report of seven cases and literature review.
Mod Rheumatol. 2020 Nov;30(6):1082-1083. doi: 10.1080/14397595.2019.1682795. Epub 2019 Oct 30.
Shirai T, Murakami K, Fujii H, Ishii T, Harigae H.
Comment on: Aortarctia: a rare manifestation of relapsing polychondrits.
Rheumatology (Oxford). 2020 Jul 1;59(7):1784-1785. doi:10.1093/rheumatology/keaa019.
Okazaki S, Watanabe R, Harigae H, Fujii H.
Better Retention of Abatacept Is Associated with High Rheumatoid Factor: A Five-Year Follow-Up Study of Patients with Rheumatoid Arthritis.
Tohoku J Exp Med. 2020 Mar;250(3):153-159. doi: 10.1620/tjem.250.153.
Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, Kakuta Y, Kanazawa Y, Masamune A, Saiki Y, Harigae H, Fujii H.
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.
Nat Commun. 2020 Mar 9;11(1):1253. doi: 10.1038/s41467-020-15088-0.
Ishii Y, Fujii H, Sugimura K, Shirai T, Hoshi Y, Fujita Y, Shirota Y, Ishii T, Shimokawa H, Harigae H.
Successful Treatment of Pulmonary Arterial Hypertension in Systemic Sclerosis with Anticentriole Antibody.
Case Rep Rheumatol. 2020 Feb 25;2020:1926908. doi: 10.1155/2020/1926908. eCollection 2020.
Shirai T, Komatsu H, Sato H, Fujii H, Ishii T, Harigae H.
Migratory Aortitis Associated with Granulocyte-colony-stimulating Factor.
Intern Med. 2020 Jun 15;59(12):1559-1563. doi: 10.2169/internalmedicine.4331-19. Epub 2020 Mar 19.
Soshi Okazaki, Ryu Watanabe, Hinako Kondo, Masataka Kudo, Hideo Harigae, Hiroshi Fujii
High Relapse Rate in Patients with Polymyalgia Rheumatica despite the Combination of Immunosuppressants and Prednisolone: A Single Center Experience of 89 patients
Tohoku J Exp Med. 2020 Jun;251(2):125-133. doi: 10.1620/tjem.251.125.
Hinako Kondo, Ryu Watanabe, Soshi Okazaki, Kaori Kuriyama, Tetsuro Ochi, Gen Yamada, Akira Sugiura, Hiromu Chiba, Akira Tsukada, Shinji Taniuchi, Takehiko Igarashi, Masataka Kudo, Hideo Harigae, Hiroshi Fujii
JAK2 mutation-positive polycythaemia vera associated with IgA vasculitis and nephrotic syndrome: a case report
Mod Rheumatol Case Rep. 2020 Jul;4(2):289-295. doi: 10.1080/24725625.2020.1728061. Epub 2020 Feb 13.
Tomoyuki Mutoh, Yuko Shirota, Azusa Ito, Hiroshi Fujii, Tomonori Ishii, Toru Nakazawa, Hideo Harigae
One after another retinal involvement in lupus
Eur J Rheumatol. 2020 Sep 3;8(2):111-112. doi: 10.5152/eurjrheum.2020.20022.
Shirai T, Shirota Y, Fujii H, Ishii T, Harigae H.
Four distinct clinical phenotypes of vasculitis affecting medium-sized arteries.
Scand J Rheumatol. 2019 Jul;48(4):308-314. doi: 10.1080/03009742.2018.1551965. Epub 2019 Jan 23.
Nakamura N, Izumi R, Hoshi Y, Takai Y, Ono R, Suzuki N, Nagai T, Ishii Y, Ishii T, Harigae H, Okada S, Aiba S, Okiyama N, Fujimoto M, Kuroda H, Tateyama M, Aoki M.
FDG-PET detects extensive calcinosis cutis in anti-NXP2 antibody-positive dermatomyositis.
Rheumatology (Oxford). 2019 Oct 1;58(10):1888. doi: 10.1093/rheumatology/kez083.
Mutoh T, Ishii T, Shirai T, Akita K, Kamogawa Y, Fujita Y, Sato H, Shirota Y, Fujii H, Harigae H.
Refractory Takayasu arteritis successfully treated with rituximab: case-based review.
Rheumatol Int. 2019 Nov;39(11):1989-1994. doi: 10.1007/s00296-019-04390-w. Epub 2019 Aug 6.
Akaishi T, Yasaka K, Abe M, Fujii H, Watanabe M, Shirai T, Ishizawa K, Takayama S, Kagaya Y, Harigae H, Ishii T.
Protein-losing gastroenteropathy with severe hypoalbuminemia associated with Sjögren's syndrome: A case report and review of the literature.
J Gen Fam Med. 2019 Oct 16;21(1):24-28. doi: 10.1002/jgf2.281. eCollection 2020 Jan.
Ishii T, Tanaka Y, Kawakami A, Saito K, Ichinose K, Fujii H, Shirota Y, Shirai T, Fujita Y, Watanabe R, Chiu SW, Yamaguchi T, Harigae H
Multicenter double-blind randomized controlled trial to evaluate the effectiveness and safety of bortezomib as a treatment for refractory systemic lupus erythematosus.
Mod Rheumatol.；28：6,986-992,2018 Feb 15:1-7. doi: 10.1080/14397595.2018.1432331.
Shirai T, Hanaoka R, Goto Y, Kojima I, Ishii Y, Hoshi Y, Fujita Y, Shirota Y, Fujii H, Ishii T, Harigae H.
Takayasu Arteritis Coexisting with Sclerosing Osteomyelitis.
Intern Med. 2018 Jul 1;57(13):1929-1934. doi: 10.2169/internalmedicine.0329-17. Epub 2018 Feb 9.
Machiyama T, So T, Okuyama Y, Kobayashi S, Phung HT, Asao A, Harigae H, Ishii N.
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation.
Biochem Biophys Res Commun. 2018 May 15;499(3):544-550. doi: 10.1016/j.bbrc.2018.03.186. Epub 2018 Apr 2.
Ishii Y, Shirai T, Hoshi Y, Fujita Y, Shirota Y, Fujii H, Ishii T, Harigae H.
Nasal Septal Perforation in Propylthiouracil-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.
Case Rep Rheumatol. 2018 Mar 22;2018:8192021. doi: 10.1155/2018/8192021. eCollection 2018.
Ogata A, Tanaka Y, Ishii T, Kaneko M, Miwa H, Ohsawa S, Yamakawa R; SHINOBI Study Group.
Long-term safety and efficacy of weekly subcutaneous tocilizumab monotherapy in patients with rheumatoid arthritis who had an inadequate response to subcutaneous tocilizumab every other week: Results from the open-label extension of the SHINOBI study.
Mod Rheumatol. 2018 Dec 14:1-8. doi: 10.1080/14397595.2018.1533514. [Epub ahead of print] PMID: 30299202
Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Malcovati L, Cazzola M, Ogawa S, Harigae H, Igarashi K.
Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia.
Nat Immunol. 2018 Oct;19(10):1059-1070. doi: 10.1038/s41590-018-0202-3. Epub 2018 Sep 24.
Shirai T, Fujii H, Saito R, Nasu K, Kamogawa Y, Fukuhara N, Fujita Y, Shirota Y, Ishii T, Harigae H.
Relapsing polychondritis complicated with myelodysplastic syndrome is resistant to the immunosuppression: comment on the article by Dion et al.
Arthritis Rheumatol. 2017 Mar;69(3):682-683. doi: 10.1002/art.39969. Epub 2017 Feb 2.
Ikeda T, Fujii H, Nose M, Kamogawa Y, Shirai T, Shirota Y, Ishii T, Harigae H.
Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity.
Arthritis Res Ther. 2017 Aug 11;19(1):187. doi: 10.1186/s13075-017-1397-7.
Yoshida M, Watanabe R, Ishii T, Machiyama T, Akita K, Fujita Y, Shirota Y, Sugimura K, Fujii H, Shimokawa H, Harigae H.
Retrospective analysis of 95 patients with large vessel vasculitis: a single center experience.
Int J Rheum Dis. 2016 Jan;19(1):87-94. doi: 10.1111/1756-185X.12777.
Nakamura K, Kawakami T, Yamamoto N, Tomizawa M, Fujiwara T, Ishii T, Harigae H, Ogasawara K.
Activation of the NLRP3 inflammasome by cellular labile iron.
Exp Hematol. 2016 Feb;44(2):116-24.
Saito S, Ishii T, Kamogawa Y, Watanabe R, Shirai T, Fujita Y, Shirota Y, Fujii H, Ito K, Shimokawa H, Yamaguchi T, Kawaguchi Y, Harigae H.
Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study.
Tohoku J Exp Med. 2016.Jan;238(1):39-47.
Koga Tomohiro , Okada Akitomo , Fukuda Takaaki, Hidaka Toshihiko, Ishii Tomonori ,Ueki Yukitaka, Kodera Takao, Nakashima Munetoshi ,Takahashi Yuichi , Honda Seiyo ,Horai Yoshiro, Watanabe Ryu, Okuno Hiroshi, AramakiToshiyuki, IzumiyamaTomomasa ,Takai Osamu ,Miyashita Taiichiro ,Sato Shuntaro, Kawashiri, Shin-ya, Iwamoto Naoki, Ichinose Kunihiro, Tamai Mami, Origuchi Tomoki, Nakamura Hideki ,Aoyagi Kiyoshi, Eguchi Katsumi, KawakamiAtsushi the Japanese RA Patients with RRP Study Group
Prognostic Factors Toward Clinically Relevant Radiographic Progression in Patients With Rheumatoid Arthritis in Clinical Practice: A Japanese Multicenter, Prospective Longitudinal Cohort Study for Achieving a Treat-to-Target Strategy.
Medicine (Baltimore). 2016 Apr;95(17):e3476. doi: 10.1097/MD.0000000000003476.
Saito S, Ishii T, Kamogawa Y, Watanabe R, Shirai T, Fujita Y, Shirota Y, Fujii H, Ito K, Shimokawa H, Yamaguchi T, Kawaguchi Y, Harigae H.
Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study.
Tohoku J Exp Med. 2016;238(1):39-47. doi: 10.1620/tjem.238.39.
Baba T, Kanno S, Shijo T, Nishio Y, Iizuka O, Kamimura N, Ishii T, Mori E.
Callosal Disconnection Syndrome Associated with Relapsing Polychondritis.
Intern Med. 2016;55(9):1191-3. doi: 10.2169/internalmedicine.55.5345.
Epub 2016 May 1.
Tomiyama F, Watanabe R, Ishii T, Kamogawa Y, Fujita Y, Shirota Y, Sugimura K, Fujii H, Harigae H.
High Prevalence of Acute Exacerbation of Interstitial Lung Disease in Japanese Patients with Systemic Sclerosis.
Tohoku J Exp Med. 2016;239(4):297-305. doi: 10.1620/tjem.239.297.
Hirabayashi Y, Munakata Y, Miyata M, Urata Y, Saito K, Okuno H, Yoshida M, Kodera T, Watanabe R, Miyamoto S, Ishii T, Nakazawa S, Takemori H, Ando T, Kanno T, Komagamine M, Kato I, Takahashi Y, Komatsuda A, Endo K, Murai C, Takakubo Y, Miura T, Sato Y, Ichikawa K, Konta T, Chiba N, Muryoi T, Kobayashi H, Fujii H, Sekiguchi Y, Hatakeyama A, Ogura K, Sakuraba H, Asano T, Kanazawa H, Suzuki E, Takasaki S, Asakura K, Sugisaki K, Suzuki Y, Takagi M, Nakayama T, Watanabe H, Miura K, Mori Y; Michinoku Tocilizumab Study Group.
Clinical and structural remission rates increased annually and radiographic progression was continuously inhibited during a 3-year administration of tocilizumab in patients with rheumatoid arthritis: A multi-center, prospective cohort study by the Michinoku Tocilizumab Study Group.
Mod Rheumatol. 2016 Nov;26(6):828-835. doi: 10.3109/14397595.2016.1160991. Epub 2016 Apr 21.
Shoji N, Endo Y, Iikubo M, Ishii T, Harigae H, Aida J, Sakamoto M, Sasano T.
Dentin hypersensitivity-like tooth pain seen in patients receiving steroid therapy: An exploratory study.
J Pharmacol Sci. 2016 Nov;132(3):187-191.
doi: 10.1016/j.jphs.2016.10.004. Epub 2016 Oct 24.
Inui M, Sugahara-Tobinai A, Fujii H, Itoh-Nakadai A, Fukuyama H, Kurosaki T, Ishii T, Harigae H, Takai T.
Tolerogenic immunoreceptor ILT3/LILRB4 paradoxically marks pathogenic autoantibody-producing plasmablasts and plasma cells in non-treated SLE.
Int Immunol. 2016 Dec;28(12):597-604. doi: 10.1093/intimm/dxw044. Epub 2016 Oct 14.
Watanabe R, Ishii T, Araki K, Ishizawa M, Kamogawa Y, Fujita Y, Shirota Y, Fujii H, Harigae H
Successful multi-target therapy using corticosteroid, tacrolimus, cyclophosphamide, and rituximab for rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis.
Mod Rheumatol. 2015 Feb 20:1-6.
Watanabe R, Fujii H, Kamogawa Y, Nakamura K, Shirai T, Ishii T, Harigae H
Chronic lupus peritonitis is characterized by the ascites with a large content of interleukin-6.
Tohoku J Exp Med. 2015; 235(4):289-94.doi: 10.1620/tjem.235.289.
Ryu Watanabe, Tomonori Ishii, Hideo Harigae
Pretreatment Screening for Hepatitis B Virus Infection in Patients with Systemic Lupus Erythematosus
Tohoku J. Exp. Med. , 2015, September 237, 9-15
Tomiyama F, Watanabe R, Fujii H, Kamogawa Y, Fujita Y, Shirota Y, Nakamichi T, Sato H, Ishii T, Harigae H
Synovitis in a Patient with IgG4-related Disease
Intern Med. 2015;54(11):1427-32.doi:10.2169/internalmedicine.54.4320
Watanabe R, Ishii T, Yoshida M, Takada N, Yokokura S, Shirota Y, Fujii H, Harigae H.
Ulcerative keratitis in patients with rheumatoid arthritis in the modern biologic era: a series of eight cases and literature review.
Int J Rheum Dis. 2015 Jul 14. doi: 10.1111/1756-185X.12688.
Tomiyama F, Watanabe R, Fujii H, Kamogawa Y, Fujita Y, Shirota Y, Nakamichi T, Sato H, Ishii T, Harigae H
Synovitis in a Patient with IgG4-related Disease
Intern Med. 2015;54(11):1427-32.doi:10.2169/internalmedicine.54.4320
Ishizuka M, Watanabe R, Ishii T, Machiyama T, Akita K, Fujita Y, Shirota Y, Fujii H, Harigae H
Long-term follow-up of 124 patients with polymysitis and dermatomyositis: Statistical analysis of prognostic factors
Mod Rheumatol. 2015 jun 13:1-6
Watanabe R, Ishii T, Nakamura K, Shirai T, Fujii H, Saito S, Harigae H.
Ulcerative colitis is not a rare complication of Takayasu arteritis.
Mod Rheumatol. 2014 Mar;24(2):372-373.
Watanabe R, Fujii H, Ishii T, Harigae H.
Calcified iliopsoas abscess caused by Enterococcus faecalis.
Intern Med. 2014;53(4):345.
Watanabe R, Fujii H, Shirai T, Saito S, Hatakeyama A, Sugimura K, Fukumoto Y, Ishii T, Harigae H.
Successful use of intensive immunosuppressive therapy for treating simultaneously occurring cerebral lesions and pulmonary arterial hypertension in a patient with systemic lupus erythematosus.
Intern Med. 2014;53(6):627-631.
Watanabe R, Hiroshi F, Shirai T, Saito S, Ishii T, Harigae H.
Autophagy plays a protective role as an anti-oxidant system in human T cells and represents a novel strategy for induction of T-cell apoptosis.
Eur J Immunol. 2014 May 5.
Watanabe R, Ishii T, Kobayashi H, Asahina I, Takemori H, Izumiyama T, Oguchi Y, Urata Y, Nishimaki T, Chiba K, Komatsuda A, Chiba N, Miyata M, Takagi M, Kawamura O, Kanno T, Hirabayashi Y, Konta T, Ninomiya Y, Abe Y, Murata Y, Saito Y, Ohira H, Harigae H, Sasaki T.
Prevalence of hepatitis B virus infection in patients with rheumatic diseases in tohoku area: a retrospective multicenter survey.
Tohoku J Exp Med. 2014;233(2):129-33.
Fujii Hiroshi, Ishii Tomonori, Hideo Harigae
Cancelled 3-C-W39-5-O/P
The 43rd Annual Meeting of The Japanese Society for Immunology Vol.43, 2014 :164
Takada N, Watanabe R, Fujii H, Kamogawa Y, Fujita Y, Shirota Y, Saito S, Ishii T, Harigae H
Pseudothrombocytosis caused by cryogloblin crystals in a patient with primary Sjogren’s syndrome.
Mod Rheumatol. 2014 Jun 20:1-2.
Sanpei S, Watanabe R, Ishii T, Harigae H
Granulomatosis with polyangiitis preceded by central diabetes insipidus.
Intern Med. 2014; 53(15):1725-6. Epub 2014 Aug 1.
フローサイトメトリーを用いたヒトプライマリーT細胞におけるオートファジーの定量及び機能解析(原著論文)
渡部 龍(東北大学 医学系研究科血液免疫病学分野), 藤井 博司, 白井 剛志, 石井 智徳, 張替 秀郎
Proceedings of Clinical Electron Microscopy 32巻 Page21-27(2014.02)